OR2T12

Across TCGA cell cohorts, OR2T12 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2T12-associated genes across cancer lineages are MYF5, CSN1S1, and C9orf57. Each is linked with OR2T12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T12-to-partner and partner-to-OR2T12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by OR2T12-low versus OR2T12-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T12→partner) and Y-score (partner→OR2T12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MYF5 →	+0.023	+5.169	<.001	.005	3	1
LUNG_SCLC	CSN1S1 →	+0.057	+3.232	<.001	.008	3	1
LUNG_SCLC	C9orf57 →	+0.043	+3.256	<.001	.005	3	1
LUNG_NSCLC_LUAD	OOSP4B →	+0.017	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MYF5 by OR2T12 expression — BREAST

Explore this box plot interactively →