OR2T10

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2T10 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2T10-associated genes across cancer lineages are Notch1, ACC_pS79, and Syk. Each is linked with OR2T10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T10-to-partner and partner-to-OR2T10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T10→partner) and Y-score (partner→OR2T10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.255+2.817<.001.03632
LUSCACC_pS79 →-0.399-3.312.015.01022
LUADSyk →+0.333+3.169.039.01931
SKCMSF2 →-0.131-2.966.028.03431
UCECMyosin-IIa_pS1943 →+0.218+2.183.044.03531
UCECKu80 →+0.248+2.183.045.03521
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration