Across TCGA cell cohorts, OR2T10 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2T10-associated genes across cancer lineages are IZUMO2, KRTAP17-1, and GALNTL5. Each is linked with OR2T10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T10-to-partner and partner-to-OR2T10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T10→partner) and Y-score (partner→OR2T10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	IZUMO2 →	+0.043	+4.906	<.001	.006	3	1
OESOPHAGUS	KRTAP17-1 →	+0.023	+4.906	<.001	.006	3	1
URINARY_TRACT	GALNTL5 →	+0.049	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	IFNG →	+0.023	+3.362	<.001	.007	3	1
LUNG_NSCLC_LUAD	CCER1 →	+0.050	+3.343	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

OR2T10 survival (RNA) · tumor vs normal (RNA) · all OR2T10 data types