OR2T1

Across TCGA cell cohorts, OR2T1 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR2T1-associated genes across cancer lineages are C10orf71, OR8B2, and CD300H. Each is linked with OR2T1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T1-to-partner and partner-to-OR2T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf71 grouped by OR2T1-low versus OR2T1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T1→partner) and Y-score (partner→OR2T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	C10orf71 →	+0.013	+4.643	<.001	.008	3	2
LUNG_NSCLC_LUAD	OR8B2 →	+0.089	+5.189	<.001	<.001	3	2
LUNG_SCLC	CD300H →	+0.099	+3.169	<.001	.005	3	2
SKIN	PKN3 →	+1.069	+3.212	.006	.006	3	2
LUNG_NSCLC_LUSC	NOBOX →	+0.040	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	PF4V1 →	+0.296	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

C10orf71 by OR2T1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →