OR2S2

Across TCGA cell cohorts, OR2S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 820 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OR2S2-associated GO terms across cancer lineages are Regulation of cell-matrix adhesion, Positive regulation of supramolecular fiber organization, and Negative regulation of amino acid biosynthetic process. Each is linked with OR2S2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR2S2-to-partner and partner-to-OR2S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-matrix adhesion grouped by OR2S2-low versus OR2S2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2S2→partner) and Y-score (partner→OR2S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-matrix adhesion →	+0.193	+0.244	<.001	.004	3	5
BONE	Positive regulation of supramolecular fiber organization →	+0.106	+0.245	<.001	.004	3	5
BONE	Negative regulation of amino acid biosynthetic process →	+0.353	+0.231	<.001	.008	3	5
BONE	Negative regulation of amino acid metabolic process →	+0.353	+0.231	<.001	.008	3	5
BREAST	Cellular response to environmental stimulus →	+0.035	+0.062	.002	.009	3	4
BONE	Regulation of cell-substrate adhesion →	+0.169	+0.245	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 820 associations by consensus.

Regulation of cell-matrix adhesion by OR2S2 expression — BONE

Explore this box plot interactively →