OR2M5

Across TCGA patient cohorts, OR2M5 mutation is significantly associated with the RNA expression of many other genes, with 2,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M5-associated genes across cancer lineages are ATP5MC1, PDP2, and NDUFAB1. Each is linked with OR2M5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2M5-to-partner and partner-to-OR2M5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5MC1 grouped by OR2M5-low versus OR2M5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M5→partner) and Y-score (partner→OR2M5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP5MC1 →	+0.446	+2.828	.001	.001	3	3
UCEC	PDP2 →	+0.333	+3.938	.006	<.001	3	3
UCEC	NDUFAB1 →	+0.486	+2.445	<.001	<.001	3	3
UCEC	MCUR1 →	+0.332	+2.413	.009	<.001	3	3
UCEC	PLEKHH3 →	+0.434	+1.673	.004	.007	3	3
UCEC	DAZAP1 →	+0.328	+2.032	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,209 associations by consensus.

ATP5MC1 by OR2M5 expression — UCEC

Explore this box plot interactively →