OR2M5

Across TCGA pan-cancer cohorts, OR2M5 RNA is linked to patient survival in 7 of 34 cancer types, making it a survival-associated OR2M5 data layer compared with 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR2M5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2M5 expression acts as an unfavorable survival marker.

HNSC, BLCA, and SKCM are the cancer types where OR2M5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.353	0.718	<.001	60	view →
BLCA	DFS	Tertile	IV	0.087	0.480	<.001	54	view →
SKCM	OS	Tertile	II,III,IV	0.174	0.843	<.001	48	view →
SCLC	OS	Tertile	All	0.192	0.713	.001	36	view →
LUSC	OS	Tertile	All	0.168	0.659	.027	27	view →
SARC	OS	Tertile	All	0.159	0.772	<.001	27	view →
STAD	DFS	Tertile	All	0.494	0.667	.013	24	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR2M5–HNSC (OS)

Open the HNSC breakdown →