OR2M5

Across TCGA cell cohorts, OR2M5 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2M5-associated genes across cancer lineages are CCDC83, OR56A4, and OR2A25. Each is linked with OR2M5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M5-to-partner and partner-to-OR2M5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC83 grouped by OR2M5-low versus OR2M5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M5→partner) and Y-score (partner→OR2M5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCDC83 →	+0.018	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR56A4 →	+0.163	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR2A25 →	+0.043	+3.760	<.001	.008	3	1
LARGE_INTESTINE	LGI1 →	+0.323	+3.029	.001	.006	3	1
LARGE_INTESTINE	OR12D3 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	GPR42 →	+0.002	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

CCDC83 by OR2M5 expression — SKIN

Explore this box plot interactively →