OR2M1P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2M1P mutation is significantly associated with the RNA expression of many other genes, with 460 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M1P-associated genes across cancer lineages are RNU1-6P, DNAI4, and CDT1. Each is linked with OR2M1P in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2M1P-to-partner and partner-to-OR2M1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-6P grouped by OR2M1P-low versus OR2M1P-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M1P→partner) and Y-score (partner→OR2M1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU1-6P →+0.625+4.578<.001.00833
UCECDNAI4 →-0.901-3.459.003.00532
UCECCDT1 →+0.835+2.617.002.00632
UCECCHAF1A →+0.658+2.606.003.00632
UCECZWILCH →+0.597+2.595.004.00632
UCECZBTB8OS →+0.357+2.617.007.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

RNU1-6P by OR2M1P expression — HNSC

Box plot of RNU1-6P in OR2M1P-low vs OR2M1P-high samples in HNSC.

Explore this box plot interactively →

Exploration