OR2L8

Across TCGA cell cohorts, OR2L8 RNA expression is significantly associated with the mutation status of many other genes, with 333 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2L8-associated genes across cancer lineages are KCNG1, ALPK1, and GRIA4. Each is linked with OR2L8 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2L8-to-partner and partner-to-OR2L8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNG1 grouped by OR2L8-low versus OR2L8-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L8→partner) and Y-score (partner→OR2L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	KCNG1 →	+3.280	+0.026	.002	<.001	3	3
OVARY	ALPK1 →	+4.450	+0.038	.004	<.001	3	3
BLOOD_Myeloma	GRIA4 →	+4.807	+0.046	.006	<.001	3	2
BONE	MYH11 →	+4.169	+0.020	.008	<.001	3	2
BONE	SPAG17 →	+4.169	+0.020	.008	<.001	3	2
SOFT_TISSUE	CLCA1 →	+4.369	+0.021	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 333 associations by consensus.

KCNG1 by OR2L8 expression — OVARY

Explore this box plot interactively →