OR2L6P

Across TCGA pan-cancer cohorts, OR2L6P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated OR2L6P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher OR2L6P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2L6P expression acts as an unfavorable survival marker, although some lineages such as PAAD and LGG show a favorable association.

LUSC, COAD, and MESO are the cancer types where OR2L6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.177	0.444	<.001	147	view →
COAD	OS	Tertile	II,III,IV	0.113	0.792	<.001	81	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
KIRP	DFS	Tertile	All	0.601	0.881	<.001	69	view →
ACC	OS	Tertile	All	0.133	0.686	.004	48	view →
UCEC	DFS	Tertile	All	0.353	0.674	.001	48	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
BLCA	OS	Tertile	III,IV	0.116	0.419	<.001	33	view →
PAAD	DFS	Tertile	All	1.000	0.208	.001	33	view →
LGG	DFS	Median	All	0.798	0.680	.001	33	view →
CESC	DFS	Tertile	All	0.945	0.807	.023	30	view →
KICH	DFS	Tertile	All	0.121	0.867	.023	27	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

OR2L6P–LUSC (OS)

Open the LUSC breakdown →