OR2L3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2L3 mutation is significantly associated with the RNA expression of many other genes, with 2,087 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2L3-associated genes across cancer lineages are MIR6826, RANP9, and ATF4P2. Each is linked with OR2L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2L3-to-partner and partner-to-OR2L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L3→partner) and Y-score (partner→OR2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCMIR6826 →+0.303+4.648.008.00433
COADRANP9 →+0.128+4.547<.001.00533
COADATF4P2 →+0.089+3.408<.001.00932
BRCAMIR7975 →+0.570+5.800<.001.00332
STADRNY4P14 →+0.390+3.466<.001.00532
LIHCCYCSP35 →+0.088+5.305<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,087 associations by consensus.

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