Across TCGA patient cohorts, OR2L2 mutation is significantly associated with the RNA expression of many other genes, with 3,929 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2L2-associated genes across cancer lineages are WBP11, HSPA9, and MRPL20-DT. Each is linked with OR2L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2L2-to-partner and partner-to-OR2L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L2→partner) and Y-score (partner→OR2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WBP11 →	+0.461	+2.191	.006	.002	3	4
UCEC	HSPA9 →	+0.720	+2.673	<.001	<.001	3	4
UCEC	MRPL20-DT →	+0.549	+3.601	<.001	.001	3	3
UCEC	TENM4 →	-0.795	-2.169	.003	.003	3	3
UCEC	SRFBP1 →	+0.537	+1.776	.005	.008	3	3
UCEC	RPP14 →	+0.492	+2.695	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,929 associations by consensus.

Exploration

OR2L2 survival (RNA) · tumor vs normal (RNA) · all OR2L2 data types