Across TCGA patient cohorts, OR2L2 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2L2-associated genes across cancer lineages are ACC_pS79, p27_pT157, and PCNA. Each is linked with OR2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2L2-to-partner and partner-to-OR2L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L2→partner) and Y-score (partner→OR2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.355	+1.884	.009	.030	3	2
LUSC	p27_pT157 →	-0.104	-2.431	.007	.019	3	2
LUSC	PCNA →	+0.227	+2.468	.014	.011	3	2
SKCM	eIF4G →	+0.369	+2.115	.032	.018	3	2
UCEC	IGFBP2 →	-0.570	-1.700	.025	.042	3	2
UCEC	Ku80 →	+0.319	+2.515	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

OR2L2 survival (RNA) · tumor vs normal (RNA) · all OR2L2 data types