Across TCGA cell cohorts, OR2L2 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2L2-associated genes across cancer lineages are HSFY2, OR10AG1, and CT45A9. Each is linked with OR2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2L2-to-partner and partner-to-OR2L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L2→partner) and Y-score (partner→OR2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	HSFY2 →	+0.049	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR10AG1 →	+0.023	+4.807	<.001	.006	3	1
OESOPHAGUS	CT45A9 →	+0.023	+4.392	<.001	.003	3	1
LUNG_SCLC	OR10H2 →	+0.046	+5.029	.001	.006	3	1
LUNG_SCLC	DPRX →	+0.066	+5.643	<.001	.002	3	1
STOMACH	SULT6B1 →	+0.167	+4.247	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

OR2L2 survival (RNA) · tumor vs normal (RNA) · all OR2L2 data types