OR2K2

Across TCGA cell cohorts, OR2K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 688 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR2K2-associated GO terms across cancer lineages are Regulation of synoviocyte proliferation, Positive regulation of synoviocyte proliferation, and Negative regulation of humoral immune response. Each is linked with OR2K2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2K2-to-partner and partner-to-OR2K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synoviocyte proliferation grouped by OR2K2-low versus OR2K2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2K2→partner) and Y-score (partner→OR2K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of synoviocyte proliferation →	-0.229	-0.018	.003	.003	3	3
LUNG_NSCLC_LUAD	Positive regulation of synoviocyte proliferation →	-0.229	-0.018	.003	.003	3	3
BLOOD_Lymphoma	Negative regulation of humoral immune response →	+0.223	+0.022	.002	<.001	3	3
LARGE_INTESTINE	Autonomic nervous system development →	+0.115	+0.012	<.001	.003	3	3
BLOOD_Lymphoma	Glycoprotein catabolic process →	+0.047	+0.027	.002	.006	3	3
CNS	Positive regulation of viral entry into host cell →	+0.062	+0.018	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 688 associations by consensus.

Regulation of synoviocyte proliferation by OR2K2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →