Across TCGA pan-cancer cohorts, OR2H5P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR2H5P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where OR2H5P RNA is repressed in tumor relative to normal tissue. In most cancer types OR2H5P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KICH and LUAD are the cancer types where OR2H5P tumor–normal differential expression is most reproducible.