Across TCGA pan-cancer cohorts, OR2H2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2H2 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR2H2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2H2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, COAD, and UCEC are the cancer types where OR2H2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.153	0.835	<.001	30	view →
COAD	OS	Median	III,IV	0.159	0.692	.021	12	view →
UCEC	DFS	Median	All	1.000	0.629	.025	6	view →
SKCM	DFS	Median	All	0.391	0.745	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR2H2 tumor-vs-normal RNA expression · all OR2H2 data types