Across TCGA patient cohorts, OR2G6 mutation is significantly associated with the RNA expression of many other genes, with 1,432 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2G6-associated genes across cancer lineages are BRK1, RPL31P59, and RHOA. Each is linked with OR2G6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2G6-to-partner and partner-to-OR2G6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2G6→partner) and Y-score (partner→OR2G6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	BRK1 →	+0.315	+3.483	<.001	.002	3	3
LUAD	RPL31P59 →	+0.114	+2.291	<.001	.002	3	3
UCEC	RHOA →	+0.476	+3.387	.002	.004	3	3
LUAD	GABPB1 →	+0.280	+1.933	<.001	.009	3	3
LUAD	MRPL9 →	+0.440	+3.726	<.001	<.001	3	3
LUAD	RN7SKP192 →	+0.035	+2.544	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,432 associations by consensus.

Exploration

OR2G6 survival (RNA) · tumor vs normal (RNA) · all OR2G6 data types