Across TCGA pan-cancer cohorts, OR2G6 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR2G6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where OR2G6 RNA is repressed in tumor relative to normal tissue. In most cancer types OR2G6 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and BRCA are the cancer types where OR2G6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2G6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.101	<.001	4	view →
KIRP	All	All	−0.084	.036	2	view →
BRCA	All	II,III,IV	+0.004	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR2G6 RNA expression & survival · all OR2G6 data types