Across TCGA cell cohorts, OR2G6 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR2G6-associated genes across cancer lineages are ADAM2, RETNLB, and IL22RA2. Each is linked with OR2G6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2G6-to-partner and partner-to-OR2G6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2G6→partner) and Y-score (partner→OR2G6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ADAM2 →	+0.002	+3.700	<.001	.009	3	1
SKIN	RETNLB →	+0.026	+3.562	<.001	.002	3	1
SKIN	IL22RA2 →	+0.011	+3.103	.001	.004	3	1
SKIN	TMPRSS12 →	+0.046	+3.760	<.001	<.001	3	1
BREAST	MT4 →	+0.172	+5.169	<.001	.005	3	1
BREAST	ANKRD66 →	+0.030	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

OR2G6 survival (RNA) · tumor vs normal (RNA) · all OR2G6 data types