OR2G2

Across TCGA cell cohorts, OR2G2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2G2-associated genes across cancer lineages are PRSS58, IL20, and OR11G2. Each is linked with OR2G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2G2-to-partner and partner-to-OR2G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by OR2G2-low versus OR2G2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2G2→partner) and Y-score (partner→OR2G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
LARGE_INTESTINE	IL20 →	+0.141	+3.662	.007	.009	3	1
SKIN	OR11G2 →	+0.015	+3.930	<.001	.003	3	1
LUNG_NSCLC_LUAD	LIM2 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	STATH →	+0.317	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	OCM2 →	+0.033	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

PRSS58 by OR2G2 expression — PANCREAS

Explore this box plot interactively →