Across TCGA patient cohorts, OR2F2 mutation is significantly associated with the RNA expression of many other genes, with 1,395 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR2F2-associated genes across cancer lineages are TIPIN, MTND4P33, and POLE2. Each is linked with OR2F2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2F2-to-partner and partner-to-OR2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2F2→partner) and Y-score (partner→OR2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.600	+3.721	<.001	<.001	3	3
BLCA	MTND4P33 →	+0.100	+5.899	<.001	.002	3	3
UCEC	POLE2 →	+0.613	+2.606	.005	.006	3	3
UCEC	APTX →	+0.368	+3.732	.006	<.001	3	3
SKCM	L3MBTL2 →	+0.303	+1.691	.002	.006	3	3
UCEC	UHRF1 →	+0.804	+2.595	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,395 associations by consensus.

Exploration

OR2F2 survival (RNA) · tumor vs normal (RNA) · all OR2F2 data types