OR2F2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2F2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2F2-associated genes across cancer lineages are Bak, PCNA, and NDRG1_pT346. Each is linked with OR2F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2F2-to-partner and partner-to-OR2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2F2→partner) and Y-score (partner→OR2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBak →+0.277+3.169.034.01932
LUSCPCNA →+0.257+2.816.028.03631
UCECNDRG1_pT346 →-0.610-3.000.017.03622
UCECVHL →-1.091-3.321.002.01031
SKCMASNS →+0.529+1.765.001.01331
UCECPKC-a →+0.514+3.321.015.01012
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration