Across TCGA cell cohorts, OR2F2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2F2-associated genes across cancer lineages are OOSP2, SLC10A2, and STH. Each is linked with OR2F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2F2-to-partner and partner-to-OR2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2F2→partner) and Y-score (partner→OR2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OOSP2 →	+0.232	+5.321	<.001	.005	3	1
SKIN	SLC10A2 →	+0.004	+4.437	<.001	.004	3	1
SKIN	STH →	+0.123	+4.196	<.001	.002	3	1
LUNG_NSCLC_LUAD	TAS2R9 →	+0.041	+3.695	.001	.005	3	1
LUNG_NSCLC_LUAD	OR13C9 →	+0.008	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	LHX8 →	+0.830	+3.787	.008	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OR2F2 survival (RNA) · tumor vs normal (RNA) · all OR2F2 data types