OR2D3

Across TCGA pan-cancer cohorts, OR2D3 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2D3 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher OR2D3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2D3 expression acts as an unfavorable survival marker.

THCA, BRCA, and SKCM are the cancer types where OR2D3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.043	0.950	<.001	36	view →
BRCA	OS	Median	All	0.599	0.924	<.001	34	view →
SKCM	DFS	Median	IV	0.040	0.454	.028	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR2D3–THCA (OS)

Open the THCA breakdown →