OR2D3

Across TCGA patient cohorts, OR2D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,257 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR2D3-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, Positive regulation of DNA metabolic process, and Cytoplasmic translation. Each is linked with OR2D3 in more than 15 cancer types. Because this analysis shows association rather than direction, both OR2D3-to-partner and partner-to-OR2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance via telomere lengthening grouped by OR2D3-low versus OR2D3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D3→partner) and Y-score (partner→OR2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of telomere maintenance via telomere lengthening →	+0.067	+0.137	<.001	<.001	3	16
STAD	Positive regulation of DNA metabolic process →	+0.056	+0.107	<.001	<.001	3	16
UCEC	Cytoplasmic translation →	+0.080	+0.022	<.001	.003	3	16
STAD	Methylation →	+0.049	+0.108	<.001	<.001	3	16
ESCA	Macromolecule methylation →	+0.054	+0.109	<.001	.002	3	16
STAD	Positive regulation of DNA repair →	+0.050	+0.105	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,257 associations by consensus.

Regulation of telomere maintenance via telomere lengthening by OR2D3 expression — ESCA

Explore this box plot interactively →