OR2D3

Across TCGA cell cohorts, OR2D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 367 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible OR2D3-associated GO terms across cancer lineages are Microtubule polymerization, Positive regulation of protein localization to mitochondrion, and Regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Each is linked with OR2D3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2D3-to-partner and partner-to-OR2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by OR2D3-low versus OR2D3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D3→partner) and Y-score (partner→OR2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Microtubule polymerization →	+0.051	+0.016	.007	.007	3	4
BLOOD_Lymphoma	Positive regulation of protein localization to mitochondrion →	+0.049	+0.018	.002	.005	3	4
KIDNEY	Regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator →	+0.118	+0.012	.004	.009	3	3
KIDNEY	Actin filament depolymerization →	+0.135	+0.012	.004	.009	3	3
KIDNEY	Regulation of DNA-templated transcription elongation →	+0.052	+0.012	.006	.009	3	3
KIDNEY	Geranyl diphosphate metabolic process →	-0.093	-0.012	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 367 associations by consensus.

Microtubule polymerization by OR2D3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →