OR2D3

Across TCGA cell cohorts, OR2D3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2D3-associated genes across cancer lineages are OR10K2, OR10T2, and SFTPB. Each is linked with OR2D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2D3-to-partner and partner-to-OR2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by OR2D3-low versus OR2D3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D3→partner) and Y-score (partner→OR2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10K2 →	+0.060	+4.705	<.001	.003	3	2
BLOOD_Leukemia	OR10T2 →	+1.046	+4.276	<.001	.007	3	2
LARGE_INTESTINE	SFTPB →	+0.150	+3.770	.005	.001	3	1
BLOOD_Leukemia	C20orf85 →	+0.052	+6.554	<.001	<.001	3	1
BLOOD_Leukemia	IL22 →	+0.037	+5.569	<.001	.001	3	1
BLOOD_Leukemia	ART1 →	+0.022	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR10K2 by OR2D3 expression — BLOOD_Leukemia

Explore this box plot interactively →