OR2D2

Across TCGA patient cohorts, OR2D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,170 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR2D2-associated GO terms across cancer lineages are RNA 3'-end processing, Glycerophospholipid biosynthetic process, and rRNA metabolic process. Each is linked with OR2D2 in more than 15 cancer types. Because this analysis shows association rather than direction, both OR2D2-to-partner and partner-to-OR2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 3'-end processing grouped by OR2D2-low versus OR2D2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D2→partner) and Y-score (partner→OR2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA 3'-end processing →	+0.045	+0.061	.002	<.001	2	16
STAD	Glycerophospholipid biosynthetic process →	+0.037	+0.049	<.001	<.001	3	15
ESCA	rRNA metabolic process →	+0.056	+0.070	.001	<.001	2	15
STAD	Regulation of double-strand break repair →	+0.040	+0.033	<.001	<.001	3	14
STAD	Positive regulation of double-strand break repair →	+0.038	+0.036	<.001	<.001	3	14
STAD	Regulation of microtubule-based process →	+0.035	+0.038	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,170 associations by consensus.

RNA 3'-end processing by OR2D2 expression — ESCA

Explore this box plot interactively →