OR2D2

Across TCGA patient cohorts, OR2D2 mutation is significantly associated with the RNA expression of many other genes, with 706 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2D2-associated genes across cancer lineages are LINC02348, LINC01727, and CPAMD8. Each is linked with OR2D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2D2-to-partner and partner-to-OR2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02348 grouped by OR2D2-low versus OR2D2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D2→partner) and Y-score (partner→OR2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02348 →	+0.127	+1.760	.001	.006	3	3
UCEC	LINC01727 →	+0.060	+2.280	.007	.002	3	2
UCEC	CPAMD8 →	-1.259	-3.692	.001	.001	3	2
UCEC	DDIT3 →	+0.638	+2.243	.002	.006	3	2
LUAD	LINC01257 →	+1.025	+3.106	<.001	.003	3	2
LUAD	RPS28P1 →	+0.201	+3.975	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

LINC02348 by OR2D2 expression — SKCM

Explore this box plot interactively →