OR2D2

Across TCGA cell cohorts, OR2D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 623 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OR2D2-associated GO terms across cancer lineages are Regulation of cilium-dependent cell motility, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with OR2D2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR2D2-to-partner and partner-to-OR2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium-dependent cell motility grouped by OR2D2-low versus OR2D2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2D2→partner) and Y-score (partner→OR2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of cilium-dependent cell motility →	-0.121	-0.018	.002	.004	3	4
PANCREAS	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.112	+0.036	<.001	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.090	+0.024	.004	.005	2	5
BREAST	Regulation of protein export from nucleus →	+0.118	+0.024	<.001	.007	3	4
BREAST	Regulation of cilium movement involved in cell motility →	-0.121	-0.018	.002	.004	3	4
CNS	Telomere maintenance →	+0.036	+0.019	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 623 associations by consensus.

Regulation of cilium-dependent cell motility by OR2D2 expression — BREAST

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