OR2B11

Across TCGA patient cohorts, OR2B11 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2B11-associated genes across cancer lineages are ATM, eIF4E, and Chk1. Each is linked with OR2B11 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2B11-to-partner and partner-to-OR2B11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by OR2B11-low versus OR2B11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2B11→partner) and Y-score (partner→OR2B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.518	-2.321	.007	.034	3	3
COAD	eIF4E →	+0.251	+3.025	.006	.019	3	2
COAD	Chk1 →	+0.333	+3.008	.004	.019	3	2
LUAD	Fibronectin →	+0.561	+3.000	.042	.036	3	1
LUAD	beta-Catenin →	-0.605	-3.000	.021	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.168	-2.893	.019	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ATM by OR2B11 expression — UCEC

Explore this box plot interactively →