OR2B11

Across TCGA pan-cancer cohorts, OR2B11 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated OR2B11 data layer compared with 4 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR2B11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2B11 expression acts as an unfavorable survival marker, although some lineages such as STAD and SKCM show a favorable association.

DLBC, THYM, and ACC are the cancer types where OR2B11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	III,IV	0.131	0.727	.002	94	view →
THYM	OS	Tertile	III,IV	0.229	1.000	<.001	60	view →
ACC	DFS	Tertile	III,IV	0.038	0.381	.002	36	view →
STAD	OS	Tertile	III,IV	0.709	0.352	.007	33	view →
SKCM	DFS	Quartile	II,III,IV	0.784	0.654	.007	28	view →
LUSC	OS	Median	All	0.710	0.868	.007	27	view →
HNSC	DFS	Quartile	IV	0.363	0.642	.005	23	view →
CESC	DFS	Tertile	IV	0.245	0.593	.012	18	view →
MESO	DFS	Tertile	II,III,IV	0.282	0.659	.013	12	view →
SARC	OS	Quartile	All	0.372	0.561	.009	11	view →
BRCA	OS	Tertile	All	0.948	0.914	.039	9	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

OR2B11–DLBC (OS)

Open the DLBC breakdown →