OR2B11

Across TCGA cell cohorts, OR2B11 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2B11-associated genes across cancer lineages are SMCP, GSTA5, and OR13C2. Each is linked with OR2B11 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2B11-to-partner and partner-to-OR2B11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMCP grouped by OR2B11-low versus OR2B11-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2B11→partner) and Y-score (partner→OR2B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SMCP →	+0.063	+5.643	<.001	.002	3	1
CNS	GSTA5 →	+0.054	+4.981	<.001	.008	3	1
CNS	OR13C2 →	+0.019	+5.754	<.001	.002	3	1
LARGE_INTESTINE	ACER1 →	+0.077	+3.145	.003	.004	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR2T12 →	+0.032	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

SMCP by OR2B11 expression — LUNG_SCLC

Explore this box plot interactively →