OR2AT4

Across TCGA patient cohorts, OR2AT4 mutation is significantly associated with the RNA expression of many other genes, with 263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2AT4-associated genes across cancer lineages are RNU6-552P, CICP6, and SNORA36A. Each is linked with OR2AT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AT4-to-partner and partner-to-OR2AT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-552P grouped by OR2AT4-low versus OR2AT4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AT4→partner) and Y-score (partner→OR2AT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-552P →	+0.440	+4.792	<.001	.006	3	2
LUSC	CICP6 →	+0.018	+4.652	.007	.004	3	2
UCEC	SNORA36A →	+0.556	+2.342	.001	.002	3	2
LUSC	LYZL2 →	+1.134	+4.591	<.001	.004	3	1
LUSC	OR6C71P →	+0.308	+4.919	<.001	.002	3	1
LUSC	KRTAP1-4 →	+0.497	+5.081	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 263 associations by consensus.

RNU6-552P by OR2AT4 expression — LUSC

Explore this box plot interactively →