OR2AT4

Across TCGA pan-cancer cohorts, OR2AT4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated OR2AT4 data layer compared with 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR2AT4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2AT4 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

LUAD, LIHC, and LUSC are the cancer types where OR2AT4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.268	0.680	<.001	78	view →
LIHC	DFS	Tertile	All	0.352	0.578	.001	48	view →
LUSC	OS	Tertile	III,IV	0.183	0.571	.017	39	view →
KIRC	DFS	Median	All	0.487	0.695	.001	38	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	36	view →
UCS	OS	Tertile	II,III,IV	0.231	0.634	.011	36	view →
THYM	DFS	Tertile	All	0.283	0.833	.007	24	view →
KIRP	OS	Tertile	All	0.485	0.712	.004	21	view →
PAAD	OS	Tertile	All	0.138	0.590	<.001	18	view →
SCLC	OS	Tertile	All	0.082	0.822	<.001	18	view →
GBM	DFS	Tertile	All	0.100	0.295	.026	18	view →
ESCA	OS	Quartile	III,IV	0.712	0.336	.010	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

OR2AT4–LUAD (OS)

Open the LUAD breakdown →