OR2AT4

Across TCGA patient cohorts, OR2AT4 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR2AT4-associated genes across cancer lineages are CD8+ Tcm, MPP, and Platelets. Each is linked with OR2AT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AT4-to-partner and partner-to-OR2AT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by OR2AT4-low versus OR2AT4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AT4→partner) and Y-score (partner→OR2AT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CD8+ Tcm →	+0.045	+3.729	.037	.021	3	2
LUSC	MPP →	+0.013	+3.694	.002	.027	3	2
LUSC	Platelets →	+0.034	+4.312	<.001	.007	3	2
UCEC	Myocytes →	+0.040	+3.246	.007	.008	3	2
SKCM	NKT →	-0.121	-3.150	.014	.019	3	1
UCEC	Erythrocytes →	+0.036	+2.393	.001	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CD8+ Tcm by OR2AT4 expression — LUSC

Explore this box plot interactively →