OR2AT4

Across TCGA cell cohorts, OR2AT4 mutation is significantly associated with the mutation status of many other genes, with 491 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2AT4-associated genes across cancer lineages are HNF4A, FGL1, and GCLC. Each is linked with OR2AT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AT4-to-partner and partner-to-OR2AT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNF4A grouped by OR2AT4-low versus OR2AT4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AT4→partner) and Y-score (partner→OR2AT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HNF4A →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	FGL1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	GCLC →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	GLT8D2 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	STAMBP →	+4.523	+5.087	.006	.006	1	2
SKIN	RASGEF1C →	+5.824	+5.824	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 491 associations by consensus.

HNF4A by OR2AT4 expression — LARGE_INTESTINE

Explore this box plot interactively →