OR2AK2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2AK2 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2AK2-associated genes across cancer lineages are LKB1, Caspase-8, and Cyclin-B1. Each is linked with OR2AK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AK2-to-partner and partner-to-OR2AK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AK2→partner) and Y-score (partner→OR2AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCLKB1 →-0.134-3.654.034.00132
UCECCaspase-8 →-0.267-3.673.015.00132
UCECCyclin-B1 →+0.502+2.999.041.03532
SKCMC-Raf →+0.177+3.000.026.03632
LUSCVEGFR2 →+0.354+2.612.002.00531
LUSCBeclin →-0.115-3.000.046.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration