Across TCGA cell cohorts, OR2AK2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2AK2-associated genes across cancer lineages are TEX50, LCN1, and OR10G3. Each is linked with OR2AK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AK2-to-partner and partner-to-OR2AK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AK2→partner) and Y-score (partner→OR2AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TEX50 →	+0.030	+4.643	<.001	.004	3	2
LUNG_NSCLC_LUAD	LCN1 →	+0.056	+3.544	<.001	.009	3	2
LUNG_SCLC	OR10G3 →	+0.047	+4.643	<.001	.004	3	1
LUNG_SCLC	SPATA31D1 →	+0.632	+4.643	<.001	.004	3	1
LUNG_SCLC	ASIC5 →	+0.119	+4.269	<.001	.005	3	1
LUNG_NSCLC_LUAD	KCNA10 →	+0.070	+3.977	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

OR2AK2 survival (RNA) · tumor vs normal (RNA) · all OR2AK2 data types