Across TCGA patient cohorts, OR2A5 mutation is significantly associated with the RNA expression of many other genes, with 1,372 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2A5-associated genes across cancer lineages are FAM230F, C10orf143, and CDKN2D. Each is linked with OR2A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2A5-to-partner and partner-to-OR2A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A5→partner) and Y-score (partner→OR2A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FAM230F →	+0.011	+2.871	<.001	.004	3	3
UCEC	C10orf143 →	-0.411	-3.459	.001	.005	3	3
SKCM	CDKN2D →	+0.334	+1.488	.003	<.001	3	3
UCEC	RRP12 →	+0.413	+3.330	.008	.005	3	3
UCEC	POC1A →	+0.654	+4.000	.003	<.001	3	3
LGG	MIR508 →	+0.278	+7.977	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,372 associations by consensus.

Exploration

OR2A5 survival (RNA) · tumor vs normal (RNA) · all OR2A5 data types