OR2A3P

Across TCGA pan-cancer cohorts, OR2A3P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated OR2A3P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR2A3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR2A3P expression acts as an unfavorable survival marker, although some lineages such as KIRC and CESC show a favorable association.

DLBC, KIRC, and READ are the cancer types where OR2A3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	III,IV	0.074	0.984	.003	57	view →
KIRC	DFS	Tertile	III,IV	0.787	0.537	.011	44	view →
READ	DFS	Tertile	IV	0.246	0.713	<.001	42	view →
ESCA	DFS	Tertile	II,III,IV	0.133	0.900	.007	33	view →
SKCM	DFS	Quartile	IV	0.132	0.598	.003	27	view →
LGG	DFS	Tertile	All	0.273	0.760	<.001	24	view →
COAD	OS	Tertile	II,III,IV	0.313	0.596	.007	15	view →
KICH	DFS	Tertile	IV	0.317	0.923	.038	9	view →
ACC	OS	Tertile	All	0.149	0.686	.047	9	view →
CESC	DFS	Tertile	II,III,IV	0.875	0.663	.043	6	view →
THCA	OS	Tertile	III,IV	0.934	0.985	.008	4	view →
LUSC	DFS	Tertile	II,III,IV	0.241	0.422	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

OR2A3P–DLBC (DFS)

Open the DLBC breakdown →