Across TCGA patient cohorts, OR2A25 mutation is significantly associated with the RNA expression of many other genes, with 1,307 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR2A25-associated genes across cancer lineages are UCK1, LMNB2, and KIF18B. Each is linked with OR2A25 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2A25-to-partner and partner-to-OR2A25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A25→partner) and Y-score (partner→OR2A25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UCK1 →	+0.478	+3.346	.002	.005	3	3
SKCM	LMNB2 →	+0.404	+1.638	.001	<.001	3	3
SKCM	KIF18B →	+0.500	+2.440	<.001	.001	3	3
SKCM	NUP62 →	+0.213	+2.204	.007	.008	3	3
SKCM	SEC22C →	+0.301	+1.623	.009	.005	3	3
SKCM	KIFC1 →	+0.413	+2.098	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,307 associations by consensus.

Exploration

OR2A25 survival (RNA) · tumor vs normal (RNA) · all OR2A25 data types