Across TCGA pan-cancer cohorts, OR2A25 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR2A25’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OR2A25 RNA is repressed in tumor relative to normal tissue. In most cancer types OR2A25 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA and UCEC are the cancer types where OR2A25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2A25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.074	<.001	6	view →
UCEC	All	II,III,IV	−0.093	.046	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: OR2A25 RNA expression & survival · all OR2A25 data types