Across TCGA patient cohorts, OR2A14 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2A14-associated genes across cancer lineages are Notch1, XBP1, and eEF2. Each is linked with OR2A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A14-to-partner and partner-to-OR2A14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A14→partner) and Y-score (partner→OR2A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.196	+2.335	.001	.018	3	2
UCEC	XBP1 →	-0.195	-1.861	.002	.049	3	2
UCEC	eEF2 →	+0.472	+2.700	.003	.006	3	1
UCEC	ERK2 →	+0.233	+2.321	.007	.033	3	1
UCEC	ETS-1 →	+0.295	+2.459	.039	.019	3	1
UCEC	JNK2 →	+0.259	+2.700	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

OR2A14 survival (RNA) · tumor vs normal (RNA) · all OR2A14 data types