OR2A1-AS1

Across TCGA pan-cancer cohorts, OR2A1-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated OR2A1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR2A1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated OR2A1-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and UCS show a favorable association.

ACC, UCS, and READ are the cancer types where OR2A1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.693	0.256	.002	32	view →
UCS	OS	Median	II,III,IV	0.719	0.307	.002	30	view →
READ	OS	Median	IV	1.000	0.677	.008	27	view →
LGG	OS	Quartile	All	0.855	0.938	.001	26	view →
LAML	DFS	Quartile	All	0.419	0.697	.003	24	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	22	view →
SARC	DFS	Quartile	All	0.687	0.530	.015	16	view →
ESCA	DFS	Median	II,III,IV	1.000	0.452	.023	14	view →
UVM	DFS	Tertile	All	0.666	0.412	.036	12	view →
BRCA	DFS	Tertile	All	0.972	0.927	.007	12	view →
OV	OS	Median	All	0.864	0.816	.020	12	view →
HNSC	DFS	Median	IV	0.699	0.584	.021	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

OR2A1-AS1–ACC (DFS)

Open the ACC breakdown →