OR1L8

Across TCGA cell cohorts, OR1L8 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR1L8-associated genes across cancer lineages are UTF1, LGALS16, and CLEC2A. Each is linked with OR1L8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1L8-to-partner and partner-to-OR1L8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTF1 grouped by OR1L8-low versus OR1L8-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L8→partner) and Y-score (partner→OR1L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	UTF1 →	+0.046	+4.906	<.001	.006	3	1
OESOPHAGUS	LGALS16 →	+0.046	+4.906	<.001	.006	3	1
LUNG_SCLC	CLEC2A →	+0.107	+5.029	<.001	.006	3	1
BLOOD_Leukemia	SPATA19 →	+0.030	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	OR6B3 →	+0.022	+5.539	<.001	.003	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

UTF1 by OR1L8 expression — OESOPHAGUS

Explore this box plot interactively →