OR1L6

Across TCGA patient cohorts, OR1L6 mutation is significantly associated with the RNA expression of many other genes, with 718 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR1L6-associated genes across cancer lineages are LINC01162, UBC, and DOLPP1. Each is linked with OR1L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1L6-to-partner and partner-to-OR1L6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01162 grouped by OR1L6-low versus OR1L6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L6→partner) and Y-score (partner→OR1L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01162 →	+0.200	+5.693	.004	.003	3	2
UCEC	UBC →	+0.548	+3.470	.001	.003	3	2
UCEC	DOLPP1 →	+0.610	+3.346	.004	.005	3	2
UCEC	PHLPP2 →	+0.399	+3.491	.009	.002	3	2
UCEC	MAST2 →	+0.486	+3.577	.007	.002	3	2
UCEC	CDC6 →	+0.760	+3.330	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 718 associations by consensus.

LINC01162 by OR1L6 expression — COAD

Explore this box plot interactively →