OR1L3

Across TCGA patient cohorts, OR1L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,776 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR1L3-associated GO terms across cancer lineages are Cellular response to topologically incorrect protein, Regulation of Ras protein signal transduction, and Macromolecule methylation. Each is linked with OR1L3 in more than 16 cancer types. Because this analysis shows association rather than direction, both OR1L3-to-partner and partner-to-OR1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to topologically incorrect protein grouped by OR1L3-low versus OR1L3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L3→partner) and Y-score (partner→OR1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular response to topologically incorrect protein →	+0.060	+0.084	<.001	<.001	3	17
STAD	Regulation of Ras protein signal transduction →	+0.050	+0.090	<.001	<.001	3	17
STAD	Macromolecule methylation →	+0.054	+0.088	<.001	<.001	3	17
ESCA	RNA modification →	+0.065	+0.116	<.001	<.001	3	17
STAD	Cytoskeleton-dependent intracellular transport →	+0.046	+0.097	<.001	<.001	3	16
STAD	Endoplasmic reticulum unfolded protein response →	+0.061	+0.093	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,776 associations by consensus.

Cellular response to topologically incorrect protein by OR1L3 expression — STAD

Explore this box plot interactively →